Lecture 3 Gene transcription Part3 mRNA processing

In this lecture segment we examine post-transcriptional mRNA processing after RNA polymerase release focusing on key steps including 5 capping m⁷GpppN formation via the unique 55 triphosphate linkage 3 poly-A tailing addition of 200300 adenylates and splicing intron removal with lariat formation to join exons. We also explore RNA editing mechanismsboth template-independent ADAR: A-to-I via inosine formation APOBEC family and template-dependent Trypanosoma brucei GUIDE RNAs for U insertiondeletionand assess their critical roles in human biology.,

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